Computational Model Aids Drug Design
This is a news story, published by Phys Org, that relates primarily to the University of Tsukuba news.
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Beyond the crystal: Dynamic model captures loop flexibility in swine virus drug design

89% Informative
Researchers at the University of Tsukuba and Mahidol University developed a refined model of the PRRSV receptor domain CD163-SRCR5 .
The model revealed a novel groove-like pocket not visible in the crystal structure, enabling more accurate prediction of small-molecule binding.
The findings offer a powerful computational solution for structure-based drug discovery beyond conventional targets.
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