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Beyond the crystal: Dynamic model captures loop flexibility in swine virus drug design

Phys Org
Summary
Nutrition label

89% Informative

Researchers at the University of Tsukuba and Mahidol University developed a refined model of the PRRSV receptor domain CD163-SRCR5 .

The model revealed a novel groove-like pocket not visible in the crystal structure, enabling more accurate prediction of small-molecule binding.

The findings offer a powerful computational solution for structure-based drug discovery beyond conventional targets.

VR Score

93

Informative language

97

Neutral language

11

Article tone

formal

Language

English

Language complexity

90

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not offensive

Hate speech

not hateful

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Known propaganda techniques

not detected

Time-value

long-living

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