Guardian
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University of Sydney researchers reviewed the findings from 15 trials involving 1,369 participants to assess how antidepressants impact pain relief and adverse events in older adults.
The researchers found a lack of evidence to support the use of antidepressants for treating most pain conditions in older people.
The study authors recognised that pain may lead to depression and that antidepressants may be used by some doctors to address both conditions, but said the benefit when used primarily for pain relief was small.